Guey-Jen Lee-Chen Selected Research

trkB Receptor

10/2020

LMDS-1, a potential TrkB receptor agonist provides a safe and neurotrophic effect for early-phase Alzheimer's disease.

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Guey-Jen Lee-Chen Research Topics

Disease

26	Parkinson Disease (Parkinson's Disease) 01/2024 - 02/2004
25	Spinocerebellar Ataxias (Spinocerebellar Ataxia) 02/2024 - 10/2008
18	Alzheimer Disease (Alzheimer's Disease) 01/2023 - 03/2010
16	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2024 - 01/2013
10	Neuroinflammatory Diseases 02/2024 - 01/2018
10	Inflammation (Inflammations) 11/2023 - 05/2013
7	Neuroblastoma 01/2023 - 01/2009
5	Machado-Joseph Disease (Spinocerebellar Ataxia Type 3) 02/2024 - 01/2013
5	Huntington Disease (Huntington's Disease) 01/2016 - 01/2013
4	Dementia (Dementias) 01/2022 - 01/2007
3	Tauopathies 10/2022 - 01/2016
3	Cognitive Dysfunction 01/2022 - 01/2012
3	Parkinsonian Disorders (Parkinsonism) 01/2018 - 03/2010
3	Cerebral Hemorrhage 10/2012 - 10/2009
2	Gait Ataxia 07/2020 - 04/2015
2	Disease Progression 01/2019 - 06/2004
2	Amyloid Plaque 12/2018 - 02/2016
2	Cerebellar Ataxia (Dysmetria) 01/2016 - 12/2014
2	Atrophy 06/2014 - 10/2004
2	Hypertension (High Blood Pressure) 10/2012 - 04/2004
2	Spinocerebellar Ataxia 17 01/2012 - 02/2009
2	Vesico-Ureteral Reflux (Vesicoureteral Reflux) 06/2004 - 04/2004
1	Gaucher Disease (Gaucher's Disease) 01/2024
1	Memory Disorders (Memory Loss) 01/2022
1	B-Cell Lymphoma (Lymphoma, B Cell) 11/2021
1	Neuritis (Polyneuritis) 01/2020
1	Hypoxia (Hypoxemia) 01/2020
1	Ataxia (Dyssynergia) 01/2019

Drug/Important Bio-Agent (IBA)

20	polyglutamineIBA 02/2024 - 02/2009
14	TATA-Box Binding Protein (TATA-Binding Protein)IBA 01/2020 - 02/2009
13	Proteins (Proteins, Gene)FDA Link 02/2024 - 04/2008
13	tributyl phosphate (TBP)IBA 01/2020 - 10/2005
8	Amyloid (Amyloid Fibrils)IBA 01/2022 - 02/2016
6	SynucleinsIBA 01/2024 - 03/2016
6	indoleIBA 11/2023 - 08/2008
6	Brain-Derived Neurotrophic Factor (BDNF)IBA 05/2023 - 06/2007
5	MelibioseIBA 03/2021 - 05/2015
5	Lactulose (Duphalac)FDA LinkGeneric 03/2021 - 05/2015
5	tau Proteins (tau Protein)IBA 01/2021 - 01/2016
4	TrehaloseIBA 03/2021 - 04/2015
3	Reactive Oxygen Species (Oxygen Radicals)IBA 02/2024 - 01/2014
3	NC009-1 compoundIBA 11/2023 - 01/2019
3	Phosphotransferases (Kinase)IBA 01/2023 - 01/2013
3	Neuroprotective AgentsIBA 03/2021 - 01/2007
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2021 - 04/2007
3	glycyrrhizae radix et rhizomaIBA 01/2021 - 01/2018
3	TrehalaseIBA 01/2020 - 05/2015
3	Peptide Initiation Factors (Initiation Factor)IBA 01/2020 - 03/2010
3	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2019 - 07/2010
2	Interleukin-6 (Interleukin 6)IBA 02/2024 - 01/2021
2	Therapeutic UsesIBA 02/2024 - 01/2023
2	Glucosylceramidase (Glucocerebrosidase)IBA 01/2024 - 09/2007
2	Chalcone (Benzalacetophenone)IBA 11/2023 - 01/2021
2	coumarinIBA 11/2023 - 01/2021
2	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA 01/2023 - 01/2020
2	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 01/2023 - 11/2021
2	Carrier Proteins (Binding Protein)IBA 01/2023 - 10/2022
2	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 01/2021 - 01/2016
2	Apolipoproteins E (ApoE)IBA 01/2019 - 10/2009
2	UbiquitinIBA 01/2019 - 07/2010
2	EnzymesIBA 06/2016 - 06/2002
2	Transcription Factors (Transcription Factor)IBA 01/2016 - 04/2015
2	Protein Kinases (Protein Kinase)IBA 09/2015 - 10/2012
2	Leucine (L-Leucine)FDA Link 01/2013 - 01/2011
2	AtaxinsIBA 01/2013 - 02/2009
2	CholesterolIBA 10/2012 - 10/2009
2	LipidsIBA 01/2011 - 10/2009
2	LuciferasesIBA 05/2009 - 01/2009
2	DNA (Deoxyribonucleic Acid)IBA 01/2007 - 10/2003
1	NeurotoxinsIBA 01/2023
1	1-Methyl-4-phenylpyridinium (1 Methyl 4 phenylpyridinium)IBA 01/2023
1	Glycogen Synthase (Synthase I)IBA 01/2023
1	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 11/2021
1	Cyclic AMP Response Element-Binding Protein (Cyclic AMP-Responsive DNA-Binding Protein)IBA 11/2021
1	CoumarinsIBA 11/2021
1	PrebioticsIBA 03/2021
1	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 01/2021
1	InterferonsIBA 01/2021
1	FlavonesIBA 01/2021
1	ApigeninIBA 01/2021
1	QuercetinIBA 01/2021
1	6,7-dihydroxyflavoneIBA 01/2021
1	wogoninIBA 01/2021
1	AntioxidantsIBA 11/2020
1	trkB ReceptorIBA 10/2020
1	PHA 767491IBA 07/2020
1	Hypoxia-Inducible Factor 1IBA 01/2020
1	Prolyl Hydroxylases (Prolyl Hydroxylase)IBA 01/2020
1	IronIBA 01/2020
1	Oxygen (Dioxygen)IBA 01/2020
1	N-(4-hydroxyphenyl)arachidonylamide (AM404)IBA 02/2019
1	AcetylcholinesteraseIBA 01/2019
1	Dinoprostone (PGE2)FDA Link 10/2018
1	ProgranulinsIBA 01/2018
1	Plant ExtractsIBA 01/2018
1	CytokinesIBA 01/2018
1	Complementary DNA (cDNA)IBA 01/2018
1	Free RadicalsIBA 01/2018

Therapy/Procedure

6	Therapeutics 01/2023 - 01/2019
2	Chinese Traditional Medicine (Traditional Chinese Medicine) 01/2019 - 01/2016